Dave Asprey
Founder of Bulletproof
Dave Asprey is an entrepreneur who founded Bulletproof, the company behind Bulletproof Coffee, and is often credited with popularizing the word biohacking. He is CEO of Upgrade Labs, a chain of biohacking studios, hosts The Human Upgrade podcast, formerly Bulletproof Radio, and has written several books, including The Bulletproof Diet and Super Human.
Updated November 1, 2026 · 3 experiments
What Dave Asprey has tried
3 experiments we can source: 3 kept. Trying something is not recommending it; each entry says which.
Kept
Mesenchymal stem cell injectionsProcedures
Dates not stated · Recommends it to others
Has had repeated stem cell treatments; in March 2026 he underwent a Costa Rica clinic protocol that delivers mesenchymal stem cells to targeted brain regions, plus stem cell injections, and called the clinic the best hardware upgrade available.
The Human Upgrade 1389A, I injected stem cells into my penis (March 2026) · Status checked March 27, 2026 · Suggest a correction
Methylene blueDrugs
Dates not stated · Recommends it to others
Says he has used methylene blue since the early 2000s and teaches listeners how to find a dose, while warning about SSRIs, psychedelics and G6PD deficiency.
The Human Upgrade #1348, The methylene blue episode (November 2025) · Status checked November 20, 2025 · Suggest a correction
NAD+ IV therapyTherapies
Dates not stated · Does not recommend it to others
Has had about 30 NAD+ infusions over his life, including at Upgrade Labs, which he founded, and said he was still a big fan, citing much better sleep.
“I've had at least 10 IV infusions of it... actually I've probably had closer to 30 over my life.”
The Human Upgrade with Dave Asprey, Stop NAD+ Decline and Slow Down Your Aging, episode 826 (May 2021) · Status checked May 27, 2021 · Suggest a correction