Experiments
What well-known people try on themselves, and what happened.
Trying something is not recommending it. Each experiment lists who has tried it, whether they kept it or stopped and why, in their own words, and what the evidence in people shows.
Drugs
- AcarboseTried by 1 person we can source: 1 kept.Limited evidence
- AyahuascaTried by 2 people we can source: 1 kept, 1 stopped.Limited evidence
- BPC-157 and healing peptidesTried by 3 people we can source: 2 kept, 1 stopped.Not enough evidence
- CandesartanTried by 1 person we can source: 1 kept.Limited evidence
- CerebrolysinTried by 1 person we can source: 1 stopped.Not enough evidence
- DutasterideTried by 1 person we can source: 1 kept.Limited evidence
- GLP-1 drugsTried by 4 people we can source: 2 kept, 1 testing, 1 stopped.Limited evidence
- Growth hormoneTried by 2 people we can source: 1 kept, 1 stopped.Evidence against
- MetforminTried by 5 people we can source: 2 kept, 1 testing, 2 stopped.Mixed evidence
- Methylene blueTried by 2 people we can source: 2 kept.Not enough evidence
- MinoxidilTried by 1 person we can source: 1 kept.Moderate evidence
- PCSK9 inhibitorsTried by 2 people we can source: 2 kept.Moderate evidence
- PsilocybinTried by 3 people we can source: 1 kept, 1 testing, 1 stopped.Not enough evidence
- RapamycinTried by 5 people we can source: 2 kept, 1 testing, 2 stopped.Limited evidence
- SenolyticsTried by 2 people we can source: 1 kept, 1 stopped.Limited evidence
- SGLT2 inhibitorsTried by 2 people we can source: 2 kept.Limited evidence
- TadalafilTried by 1 person we can source: 1 kept.Limited evidence
- Testosterone replacement therapyTried by 2 people we can source: 2 kept.Mixed evidence
- TretinoinTried by 1 person we can source: 1 kept.Moderate evidence
Therapies
- Cold plungeTried by 2 people we can source: 2 kept.Limited evidence
- Exosome therapyTried by 1 person we can source: 1 testing.Not enough evidence
- Follistatin gene therapyTried by 2 people we can source: 2 testing.Not enough evidence
- Hyperbaric oxygen therapyTried by 3 people we can source: 2 kept, 1 testing.Limited evidence
- Intermittent hypoxia-hyperoxia (IHHT)Tried by 1 person we can source: 1 kept.Limited evidence
- Morning sunlightTried by 2 people we can source: 2 kept.Moderate evidence
- NAD+ IV therapyTried by 3 people we can source: 3 kept.Not enough evidence
- SaunaTried by 4 people we can source: 4 kept.Limited evidence
- Shockwave therapyTried by 1 person we can source: 1 kept.Not enough evidence
- Telomerase gene therapyTried by 1 person we can source: 1 testing.Not enough evidence
- Total plasma exchangeTried by 1 person we can source: 1 testing.Limited evidence
- Whole-body cryotherapyTried by 1 person we can source: 1 kept.Limited evidence
- Young plasma exchangeTried by 1 person we can source: 1 stopped.Not enough evidence
Procedures
- Blood biomarker trackingTried by 3 people we can source: 3 kept.Not enough evidence
- Donor fat injections to the faceTried by 1 person we can source: 1 stopped.Limited evidence
- Epigenetic age testsTried by 5 people we can source: 3 kept, 2 testing.Limited evidence
- Fractional laser skin resurfacingTried by 1 person we can source: 1 kept.Limited evidence
- Mesenchymal stem cell injectionsTried by 4 people we can source: 2 kept, 2 testing.Mixed evidence
- Penile BotoxTried by 1 person we can source: 1 testing.Limited evidence
- PRP for hair lossTried by 1 person we can source: 1 stopped.Mixed evidence
- Whole-body MRI screeningTried by 5 people we can source: 5 kept.Not enough evidence
Supplements
- Alpha-ketoglutarateTried by 2 people we can source: 2 kept.Not enough evidence
- CreatineTried by 5 people we can source: 5 kept.Moderate evidence
- Ketone estersTried by 2 people we can source: 2 kept.Limited evidence
- Large daily supplement stacksTried by 3 people we can source: 3 kept.Not enough evidence
- NMN and NRTried by 4 people we can source: 4 kept.Limited evidence
- ResveratrolTried by 2 people we can source: 2 kept.Mixed evidence
Devices
Diets and fasting
- Carnivore dietTried by 2 people we can source: 2 kept.Not enough evidence
- Fasting-mimicking dietTried by 1 person we can source: 1 kept.Limited evidence
- Ketogenic dietTried by 4 people we can source: 2 kept, 2 stopped.Mixed evidence
- One meal a day (OMAD)Tried by 1 person we can source: 1 kept.Mixed evidence
- Oreos to lower LDLTried by 1 person we can source: 1 stopped.Not enough evidence
- Plant-based dietTried by 1 person we can source: 1 kept.Moderate evidence
- Prolonged water fastingTried by 2 people we can source: 1 kept, 1 stopped.Not enough evidence
- Time-restricted eatingTried by 3 people we can source: 2 kept, 1 stopped.Mixed evidence