Matt Kaeberlein
Biologist of aging, former director of the Dog Aging Project
Matt Kaeberlein is a biologist who studies the biology of aging, including mTOR and rapamycin. He was a professor at the University of Washington and co-founded and co-directed the Dog Aging Project, which tests rapamycin in pet dogs. He is now CEO of Optispan, a longevity medicine company in Seattle, and hosts The Optispan Podcast.
Updated November 1, 2026 · 1 experiment · cited in 1 guide
What Matt Kaeberlein has tried
1 experiment we can source: 1 kept. Trying something is not recommending it; each entry says which.
Kept
RapamycinDrugs
Dates not stated · Does not recommend it to others
Started it to treat a frozen shoulder, which he says improved within two weeks and was 95% better by 12 weeks, and now takes it in 12-week courses with breaks of six to eight months, restarting when joint aches return.
“By the end of 12 weeks, I was 95% back to my full range of motion.”
Irish Examiner, Rapamycin: Could a simple pill add years to your life? (May 2024) · Status checked May 3, 2024 · Suggest a correction
Where our guides cite Matt Kaeberlein
Their public positions, summarized in our words. Follow each link for the full context.
Blueprint (Bryan Johnson)Mixed or cautious
Describes the longevity self-experiment scene as a signal-to-noise problem: some real signal, buried in a lot of noise.