David Sinclair
Geneticist at Harvard Medical School, author of Lifespan
David Sinclair is a professor of genetics at Harvard Medical School and co-director of its Paul F. Glenn Center for Biology of Aging Research. His lab studies sirtuins, NAD+ and epigenetic changes in aging, including attempts to reverse them in animals. He wrote Lifespan, a 2019 book arguing that aging can be treated, and has co-founded several biotech companies.
Updated November 1, 2026 · 5 experiments
What David Sinclair has tried
5 experiments we can source: 5 kept. Trying something is not recommending it; each entry says which.
Kept
Epigenetic age testsProcedures
Dates not stated · Recommends it to others
Says his calculated biological age has fallen for a decade or more; he co-founded Tally Health, which sells an at-home biological age test.
“My calculated biological age has been going down for the past decade or more”
Fortune Well, Harvard biologist claims to be a decade younger thanks to these 4 lifestyle habits (March 2023) · Status checked March 16, 2023 · Suggest a correction
Large daily supplement stacksSupplements
Dates not stated · Does not recommend it to others
Described taking about 1 g of NMN each morning with coffee and about 1 g of resveratrol stirred into yogurt, as his personal routine rather than advice.
“It is a gram of resveratrol, whatever I pour out into my yogurt.”
FoundMyFitness, Dr. David Sinclair's personal dosage and supplementation habits (November 2019) · Status checked November 7, 2019 · Suggest a correction
MetforminDrugs
Dates not stated · Does not recommend it to others
Takes 1 g a day, alternating with berberine, and skips it on days he works out.
Peter Diamandis, Updated Longevity Protocols for 2026: What David Sinclair and I Are Actually Doing (April 2026) · Status checked April 21, 2026 · Suggest a correction
NMN and NRSupplements
Dates not stated · Does not recommend it to others
Takes 1 g of NMN every morning and has for more than a decade, as part of a protocol built on his lab's research on NAD+ and aging.
Peter Diamandis, Updated Longevity Protocols for 2026: What David Sinclair and I Are Actually Doing (April 2026) · Status checked April 21, 2026 · Suggest a correction
ResveratrolSupplements
Dates not stated · Does not recommend it to others
Takes 1 g every morning, always with a little fat such as olive oil or yogurt, which he says it needs to be absorbed.
Peter Diamandis, Updated Longevity Protocols for 2026: What David Sinclair and I Are Actually Doing (April 2026) · Status checked April 21, 2026 · Suggest a correction